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PLEASANTON, Calif. , Dec. 23, 2024 /PRNewswire/ -- 10x Genomics, Inc. (Nasdaq: TXG), a leader in single cell and spatial biology, announced today it had secured a permanent injunction in the U.S. District Court for the District of Delaware against the GeoMx products sold by Bruker Corporation (Nasdaq: BRKR), which acquired the product line from NanoString Technologies. To minimize the risk of disruption to ongoing research, 10x Genomics requested a carve-out for GeoMx users who installed an instrument prior to the trial in November 2023 . The injunction, which the Court said it will enter in January 2025 , is expected to prohibit Bruker from making, using, selling or offering to sell in the United States its GeoMx Digital Spatial Profiler and associated instruments, reagents and services for RNA and protein detection. At the request of 10x Genomics, the injunction will not block ongoing research by researchers who installed a GeoMx instrument prior to November 18, 2023 . Such customers can continue to purchase GeoMx reagents for use with existing GeoMx instruments for purposes of continuing their ongoing research. The Court found that making such an exception for ongoing research strikes a "workable balance between protecting the patentee's rights and protecting the public from the injunction's adverse effects." In addition, the Court affirmed the $31 million damages awarded by the November 2023 jury verdict, as well as supplemental damages and interest that will be added to the total damages when final judgment is entered. "Today's decision helps to safeguard our decade-long investment in innovation and ensures we can continue to develop groundbreaking technologies that help our customers revolutionize science," said Eric Whitaker , Chief Legal Officer at 10x Genomics. "10x exists to fuel scientific progress – not stifle it – and that is why we've done our utmost to ensure this injunction was structured to protect both our intellectual property and existing GeoMx customers' ongoing research." The Court recognized the harm NanoString's infringing conduct caused 10x when it wrote in its ruling, "Having been careful not to license its technology, 10x suffers when it proclaims itself as an innovator in spatial genomics but a competitor is using the same innovative, patented technology." Today's Court decision follows a November 2023 jury verdict that found that NanoString's GeoMx products willfully infringed seven patents exclusively licensed to 10x Genomics by Prognosys. During the trial, the jury heard testimony from the sole inventor of the patents, Illumina co-founder Mark Chee , and NanoString CEO Brad Gray and NanoString CSO Joe Beechem. After hearing all of the evidence, the jury determined that all seven patents had been infringed by NanoString, that each patent was valid, that NanoString willfully infringed those patents and that monetary damages were owed to 10x for the infringement of all seven patents. In affirming the jury's finding that NanoString willfully infringed, the Court relied on the evidence showing that NanoString knew or was willfully blind that its acts would cause infringement of 10x's rights. The asserted patents in Case No. 21-cv-653-MFK include (a) U.S. Patent No. 10,472,669; (b) U.S. Patent No. 10,961,566; (c) U.S. Patent No. 10,983,113; (d) U.S. Patent No. 10,996,219; (e) U.S. Patent No. 11,001,878; (f) U.S. Patent No. 11,008,607 and (g) U.S. Patent No. 11,293,917. About 10x Genomics 10x Genomics is a life science technology company building products to accelerate the mastery of biology and advance human health. Our integrated solutions include instruments, consumables and software for single cell and spatial biology, which help academic and translational researchers and biopharmaceutical companies understand biological systems at a resolution and scale that matches the complexity of biology. Our products are behind breakthroughs in oncology, immunology, neuroscience and more, fueling powerful discoveries that are transforming the world's understanding of health and disease. To learn more, visit 10xgenomics.com or connect with us on LinkedIn or X (Twitter) . Forward Looking Statements This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 as contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to the "safe harbor" created by those sections. All statements included in this press release, other than statements of historical facts, may be forward-looking statements. Forward-looking statements generally can be identified by the use of forward-looking terminology such as "may," "might," "will," "should," "expect," "plan," "anticipate," "could," "intend," "target," "project," "contemplate," "believe," "see," "estimate," "predict," "potential," "would," "likely," "seek" or "continue" or the negatives of these terms or variations of them or similar terminology, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include statements regarding litigation and remedies as well as possible outcomes of litigation. These forward-looking statements do not reflect that our success will depend on our ability to obtain, maintain and protect our intellectual property rights, intellectual property litigation could be expensive, time-consuming, unsuccessful and could interfere with our ability to develop, manufacture and commercialize our products or technologies, litigation outcomes are unpredictable or there may be changes in our litigation strategy. These statements are based on management's current expectations, forecasts, beliefs, assumptions and information currently available to management. Actual outcomes and results could differ materially from these statements due to a number of factors and such statements should not be relied upon as representing 10x Genomics, Inc.'s views as of any date subsequent to the date of this press release. 10x Genomics, Inc. disclaims any obligation to update any forward-looking statements provided to reflect any change in 10x Genomics' expectations or any change in events, conditions or circumstances on which any such statement is based, except as required by law. The material risks and uncertainties that could affect 10x Genomics, Inc.'s financial and operating results and cause actual results to differ materially from those indicated by the forward-looking statements made in this press release include those discussed under the captions "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" in the company's most recently-filed 10-K for the fiscal year ended December 31, 2023 and elsewhere in the documents 10x Genomics, Inc. files with the Securities and Exchange Commission from time to time. Disclosure Information 10x Genomics uses filings with the Securities and Exchange Commission, our website ( www.10xgenomics.com ), press releases, public conference calls, public webcasts and our social media accounts as means of disclosing material non-public information and for complying with our disclosure obligations under Regulation FD. Contacts Investors: investors@10xgenomics.com Media: media@10xgenomics.com View original content to download multimedia: https://www.prnewswire.com/news-releases/us-district-court-awards-10x-genomics-permanent-injunction-in-patent-infringement-lawsuit-against-bruker-corporations-geomx-products-302338627.html SOURCE 10x Genomics, Inc. Best trending stories from the week. Success! An email has been sent to with a link to confirm list signup. Error! There was an error processing your request. You may occasionally receive promotions exclusive discounted subscription offers from the Roswell Daily Record. Feel free to cancel any time via the unsubscribe link in the newsletter you received. You can also control your newsletter options via your user dashboard by signing in.

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AVITA Medical Announces FDA Approval of RECELL GO mini, Optimizing Treatment for Smaller WoundsBy CLAIRE RUSH President-elect Donald Trump has once again suggested he wants to revert the name of North America’s tallest mountain — Alaska’s Denali — to Mount McKinley, wading into a sensitive and decades-old conflict about what the peak should be called. Related Articles National Politics | Inside the Gaetz ethics report, a trove of new details alleging payments for sex and drug use National Politics | An analyst looks ahead to how the US economy might fare under Trump National Politics | Trump again calls to buy Greenland after eyeing Canada and the Panama Canal National Politics | House Ethics Committee accuses Gaetz of ‘regularly’ paying for sex, including with 17-year-old girl National Politics | Trump wants mass deportations. For the agents removing immigrants, it’s a painstaking process Former President Barack Obama changed the official name to Denali in 2015 to reflect the traditions of Alaska Natives as well as the preference of many Alaska residents. The federal government in recent years has endeavored to change place-names considered disrespectful to Native people. “Denali” is an Athabascan word meaning “the high one” or “the great one.” A prospector in 1896 dubbed the peak “Mount McKinley” after President William McKinley, who had never been to Alaska. That name was formally recognized by the U.S. government until Obama changed it over opposition from lawmakers in McKinley’s home state of Ohio. Trump suggested in 2016 that he might undo Obama’s action, but he dropped that notion after Alaska’s senators objected. He raised it again during a rally in Phoenix on Sunday. “McKinley was a very good, maybe a great president,” Trump said Sunday. “They took his name off Mount McKinley, right? That’s what they do to people.” Once again, Trump’s suggestion drew quick opposition within Alaska. “Uh. Nope. It’s Denali,” Democratic state Sen. Scott Kawasaki posted on the social platform X Sunday night. Republican Sen. Lisa Murkowski , who for years pushed for legislation to change the name to Denali, conveyed a similar sentiment in a post of her own. “There is only one name worthy of North America’s tallest mountain: Denali — the Great One,” Murkowski wrote on X. Various tribes of Athabascan people have lived in the shadow of the 20,310-foot (6,190-meter) mountain for thousands of years. McKinley, a Republican native of Ohio who served as the 25th president, was assassinated early in his second term in 1901 in Buffalo, New York. Alaska and Ohio have been at odds over the name since at least the 1970s. Alaska had a standing request to change the name since 1975, when the legislature passed a resolution and then-Gov. Jay Hammond appealed to the federal government. Known for its majestic views, the mountain is dotted with glaciers and covered at the top with snow year-round, with powerful winds that make it difficult for the adventurous few who seek to climb it. Rush reported from Portland, Oregon.WASHINGTON (AP) — China is expanding its nuclear force , has increased military pressure against Taiwan and has strengthened its ties with Russia over the past year, according to a Pentagon report Wednesday that details actions accelerating key areas of conflict with the United States. The report, however, also notes that the recent rash of corruption allegations within China's powerful Central Military Commission , which oversees the People’s Liberation Army, is hurting Beijing’s military growth and could slow its campaign to modernize. The impact, said a senior defense official, is a bit of a mixed bag because while there has been progress in some programs, China has slid back in others. The official, who spoke on condition of anonymity to describe the U.S. assessment, warned that Beijing is working toward developing a more diverse and technologically sophisticated nuclear force . While the expected number of nuclear warheads has maintained consistent growth, China is broadening its targeting abilities. Beijing is going to be able to go after more and different types of targets, do greater damage and have more options for multiple rounds of counterstrikes, the official said. The U.S. is urging China to be more transparent about its nuclear program, while also warning that America will defend its allies and take appropriate steps in response. According to the report, which provides the annual U.S. assessment of China’s military power and is required by Congress, China had more than 600 operational nuclear warheads as of May, and the U.S. expects it will have more than 1,000 by 2030. The Chinese Embassy, in response, said China has always “firmly adhered to a nuclear strategy of self-defense,” follows the no-first-use nuclear policy and maintains its nuclear capabilities at the minimum level required for national security. Liu Pengyu, the embassy spokesman, said such annual reports by the Pentagon are “filled with ‘Cold-War' thinking and zero-sum game mentality, which China firmly opposes.” The Biden administration has worked to maintain a balance with China, building up the U.S. military presence in the Asia-Pacific region to be ready to counter Beijing while also encouraging increased communications between the two countries at the diplomatic and military levels. That uptick in talks has coincided with a decrease in coercive and risky intercepts of U.S. aircraft since late 2023, compared with the previous two years. China still, however, does what the U.S. military considers “unsafe” flights near American and allied forces in the region. The Pentagon’s national defense strategy is built around China being the greatest security challenge for the U.S. , and the threat from Beijing influences how the U.S. military is equipped and organized for the future. The corruption within the PLA has resulted in at least 15 high-ranking officials being ousted in a major shakeup of China’s defense establishment. “This wave of corruption touches every service in the PLA, and it may have shaken Beijing’s confidence," the report said. In June, China announced that former Defense Minister Li Shangfu and his predecessor, Wei Fenghe, were expelled from the ruling Communist Party and accused of corruption. Last month, another senior official, Miao Hua, was suspended and put under investigation, according to China's Defense Ministry. The U.S. report points to a persistent increased military presence by China around Taiwan, the self-governing island that China claims as its own. It said China's navy has been in the region more and that there have been increased crossings into the island's air defense identification zone and major military exercises in the area. Just last week, a large deployment of Chinese navy and coast guard vessels in the waters around Taiwan triggered alarm as Taiwanese officials said it looked like China was simulating a blockade . Officials have said there were as many as 90 ships involved in what Taiwan described as two walls designed to demonstrate that the waters belong to China. Taiwan split from communist China in 1949 and has rejected Beijing’s demands that it accept unification . China says it will do so by force if necessary, and leaders have said they want to be ready to do so by 2027. Beijing also has demanded that Washington not interfere with the Taiwan issue, citing that it is an internal matter. The United States is obligated under domestic law to help defend Taiwan and give it weapons and technology to deter invasion. The island democracy has been the chief source of tension between Washington and Beijing for decades and is widely seen as the most likely trigger for a potentially catastrophic U.S.-China war. More broadly, the report concluded that the PLA continued its drive to develop greater military capabilities but “made uneven progress toward its 2027” milestone for modernization. One area of expansion, the report said, is with unmanned aerial systems, which officials said are “quickly approaching U.S. standards.” Regarding Russia, the report said China has supported Russia's war against Ukraine and sold Russia dual-use items that Moscow's military industry relies on. Dual use items can be used for both civilian and military purposes.

In a world where technology evolves at lightning speed, investing in an older model might seem like a short term savvy way to save a few bucks. However, choosing a less expensive and outdated laptop can lead to frustration as it quickly becomes obsolete. Why settle for yesterday’s technology when you can embrace the future? The latest MacBook Pro models equipped with the new M4 and M4 Pro chips have just hit the market, and they are available at huge discounts this Black Friday. Amazon is offering great deals on several configurations of the new MacBook Pro M4 models. The entry-level 14.2-inch MacBook Pro with the M4 chip is now available for $1,399, down from its original price of $1,599 . This model is perfect for everyday tasks such as web browsing, document editing and heavy media consumption. It features 16GB of unified memory and a 512GB SSD. See MacBook Pro M4 / 16GB / 512GB at Amazon For those who require more processing power, the 14.2-inch MacBook Pro featuring the M4 Pro chip stands out as a great option. This model boasts a robust 12-core CPU and a 16-core GPU combined with 24GB of RAM and a 512GB SSD. Priced at $1,749, reduced from $1,999 , this configuration is ideal for professionals who need enhanced processing capabilities for demanding tasks such as video editing or software development. See MacBook Pro M4 Pro 14′′ / 24GB / 512GB at Amazon If additional storage is essential, consider the 14.2-inch MacBook Pro with the M4 Pro chip that comes equipped with a larger 1TB SSD: This model is currently available for $2,099 on Amazon, down from $2,399 . With its powerful specifications and enhanced storage capacity, it caters to professionals who work with large files or require extensive software libraries. See MacBook Pro M4 Pro 14′′ / 24GB / 1TB at Amazon Improved Performance, More Energy Efficiency All models feature Apple’s innovative M4/M4 Pro chip architecture that significantly enhances performance while maintaining energy efficiency. The M4 chips improve CPU and GPU performance while integrating advanced AI capabilities through Apple Intelligence. This allows for faster processing of machine learning tasks and improved graphics rendering. Battery life remains one of the most appreciated features across all models— Apple advertises up to 24 hours of usage on a single charge —which is an industry-leading achievement for laptops. The combination of powerful hardware and optimized software (thanks to these Apple-developed chips) ensures that users can work throughout the day without needing to recharge frequently. In terms of performance differences among these models, users will find that the entry-level MacBook Pro is well-suited for general use but may struggle with more intensive applications compared to its Pro counterparts: The M4 Pro models are designed for professionals who require high-performance computing capabilities, whether it’s rendering high-resolution videos or running complex simulations. One of the great aspects of these Black Friday deals is that Amazon offers an extended return policy allowing customers to return products until January 31, 2025 . This extended timeframe makes it easier for shoppers to purchase gifts without worrying about immediate returns after the holiday season. As these deals represent the first discounts seen on these new models, stock is likely to diminish quickly. See MacBook Pro M4 / 16GB / 512GB at AmazonFormer Duke QB Maalik Murphy transferring to Oregon State

Is it safe to eat turkey this Thanksgiving amid bird flu outbreak? Here’s what experts sayOTTAWA — Former Bank of Canada governor Mark Carney says Canada didn't live up to its values on immigration over the last few years as it allowed more people into the country than it could absorb. Carney, who is currently a special adviser to the Liberal party, made those comments during an event in Ottawa held by Cardus, a Christian think tank. Carney says Canada let newcomers down by admitting more workers and students than it could provide for, including with housing, health care and social services. Earlier this fall, the Liberal government announced a plan to significantly reduced its immigration target for permanent residents and to dramatically scale back the number of temporary residents in Canada. Those changes came about after a period of strong population growth that led to mounting criticism of the Liberal government's immigration policies. Prime Minister Justin Trudeau has acknowledged that the federal government did not get the balance right on immigration after the COVID-19 pandemic. This report by The Canadian Press was first published Nov. 27, 2024. Nojoud Al Mallees, The Canadian Press

Detroit (AP) — China will soon see a massive expansion of electric vehicle battery swapping, as global battery maker CATL said Wednesday it is investing heavily in stations there next year. Battery swapping is not new — but it's had a challenging journey. Adoption of electric vehicles has varied in regions across the globe over the past several years, and that doesn't always bode well for building new infrastructure. Javascript is required for you to be able to read premium content. Please enable it in your browser settings.Caitlin Clark honored as AP Female Athlete of the Year following her impact on women's sports Caitlin Clark has been named the AP Female Athlete of the Year after raising the profile of women’s basketball to unprecedented levels in both college and the WNBA. She led Iowa to the national championship game, was the top pick in the WNBA draft and captured rookie of the year honors in the league. Fans packed sold-out arenas and millions of television viewers followed her journey on and off the court. Clark's exploits also put other women's sports leagues in the spotlight. A group of 74 sports journalists from AP and its members voted on the award. Other athletes who received votes included Olympic gold medalist Simone Biles and boxer Imane Khelif. Clark’s only the fourth women’s basketball player to win the award since it was first given in 1931. Javascript is required for you to be able to read premium content. Please enable it in your browser settings. Success! An email has been sent to with a link to confirm list signup. Error! There was an error processing your request. Get the latest need-to-know information delivered to your inbox as it happens. Our flagship newsletter. Get our front page stories each morning as well as the latest updates each afternoon during the week + more in-depth weekend editions on Saturdays & Sundays.AP Business SummaryBrief at 4:40 p.m. EST

MAPUTO, Mozambique (AP) — Violence that engulfed Mozambique after the country's highest court confirmed ruling Frelimo party presidential candidate Daniel Chapo as the winner of disputed Oct. 9 elections killed at least 21 people, including two police officers, authorities said Tuesday. Mozambique Interior Minister Pascoal Ronda told a news conference in Maputo late Tuesday that a wave of violence and looting was sparked by the court's announcement a day earlier. He said it was led by mostly youthful supporters of losing candidate Venancio Mondlane, who received 24% of the vote, second to Chapo, who got 65%. “From the preliminary survey, in the last 24 hours, 236 acts of violence were recorded throughout the national territory that resulted in 21 deaths, of which two members of the Police of the Republic of Mozambique also died," Ronda said. He said 13 civilians and 12 police were injured. Ronda said 25 vehicles were set on fire, including two police vehicles. He added that 11 police subunits and a penitentiary were attacked and vandalized and 86 inmates were freed. Tensions were high in the country ahead of the The Constitutional Council ruling on Monday and violent protests started immediately after the announcement was made. Footage circulating on various social media platforms showed protesters burning and looting shops in the capital Maputo and the city of Beira, where some city officials were reported to have fled the city. Mondlane has called for a “shutdown” starting Friday but violence in the country has already escalated and the situation remained tense in the capital on Tuesday night following a day of violence and looting by protesters. The country of 34 million people has been on edge since the Oct. 9 general elections . Mondlane’s supporters, mostly hundreds of thousands of young people, have since taken to the streets, and have been met by gunfire from security forces. This brings to more than 150 the number of people who have died from post-election violence since the initial results were announced by the country's electoral body.Global Automobile Antenna Market Growth : $9.4 Billion In 2023 To $14.2 Billion By 2033 CAGR Of 4.5%

Journalist with the Times of India since August 2004, Shailvee Sharda writes on Health, Culture and Politics. Having covered the length and breadth of UP, she brings stories that define elements like human survival and its struggle, faiths, perceptions and thought processes that govern the decision making in everyday life, during big events such as an election, tangible and non-tangible cultural legacy and the cost and economics of well-being. She keenly follows stories that celebrate hope and life in general. Read More 10 ways to use pumpkin seeds 7 things that boys learn from their moms 10 Indian breakfast dishes loved across the world How to grow onion and garlic on your kitchen window Kid-friendly wildlife experiences in India How to make Chicken Chili Pakora at home 10 types of South-Indian rice dishes and how to make them 10 most beautiful offbeat places for solo travel in India (2025) Persimmon: Nutrients, health benefits of this vibrant orange colored fruit 8 animals that have more than 2 eyesPresident Bola Tinubu on Monday declared that corruption in all its ramifications, is bad for the people. Tinubu made the declaration while answering a question during his first presidential media chat about the intention of his administration to fight corruption. The Nigerian leader said increasing the minimum wage of workers in the country to ₦70,000 is part of the measures adopted to fight corruption in the country. He stressed the need to identify the root causes of corruption and deal with such causes. “Corruption in all ramifications is bad for the people, but first of all, pay attention to the causes. Why are the people corrupt? “The lack of social amenities, lack of funds, their children’s education...” “There are so many anti-corruption mechanisms that can be put in place that will help the people not to be corrupt, paying them good and living wages. I moved from ₦35,000 to ₦70,000; to me, that’s anti-corruption,” President Tinubu said. The President added that as part of measures towards fighting corruption, he has made more money available to the state and local governments and is always open about how much the government is making on a monthly basis. According to him, transparency is one of the tools used to fight corruption. Tinubu noted that it is difficult to eliminate corruption, but it can be reduced to the barest minimum by meeting the people’s needs. “It’s very difficult to say you will eliminate it (corruption), you will reduce it to the barest minimum, meet the people’s needs, ” he said.